NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: beta-caryophyllene oxide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MAPK1mitogen-activated protein kinase 15594Breast adenocarcinomaMCF-7----beta-caryophyllene oxide slightly upregulated the phosphorylation of p38 MAPK in the cancer cells.21924548
MAPK1mitogen-activated protein kinase 15594Prostate CancerPC-3----beta-caryophyllene oxide slightly upregulated the phosphorylation of p38 MAPK in the PC-3 cancer cells.21924548
MAPK1mitogen-activated protein kinase 15594Breast adenocarcinomaMCF-7----beta-caryophyllene oxide substantially induced the activation of ERK kinase at a concentration as low as 10 µM21924548
MAPK1mitogen-activated protein kinase 15594Prostate CancerPC-3----beta-caryophyllene oxide substantially induced the activation of ERK kinase at a concentration as low as 10 µM in PC-3 cancer cells.21924548

 






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