NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Andrographolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 95715Breast adenocarcinomaMCF-7----After andrographolide treatment we also observed the increased proliferation of HPBLs and the increased expression of CD3, CD4, CD8, and CD56 markers on lymphocytes14641821
PSMD9proteasome (prosome, macropain) 26S subunit, non-ATPase, 95715Breast adenocarcinomaMCF-7----Andrographolide induced the expression of p27 which is a major CDK inhibitor involved in the regulation of G1 phase of cell cycle.10679837

 






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