NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Ginsenoside Rg3

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Colon CancerSW-460----Constitutive activation of NF-kB was observed in colon cancer cells, and treat-ment with Rg3 (0-100 µM) and docetaxel (1-50 nM)concentration-dependently inhibited NF-kB activity with IC50values of about 100 µM for Rg3 or 10 nM for docetaxel.19471891
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Colon cancerHCT-116----Constitutive activation of NF-kB was observed in colon cancer cells, and treat-ment with Rg3 (0-100 µM) and docetaxel (1-50 nM)concentration-dependently inhibited NF-kB activity with IC50values of about 100 µM for Rg3 or 10 nM for docetaxel.19471891

 






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