NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 2',4'-dihydroxychalcone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
birc5abaculoviral IAP repeat-containing 5a373110Gastric CancerMGC-803----TFC significantlydecreases survivin mRNA expression. Therefore, TFC can induce the apoptosis of MGC-803 cells via down-regulation of survivin mRNA expression.20471467
CASP3caspase 3, apoptosis-related cysteine peptidase836Gastric CancerMGC-803----TFC significantly increases caspase-3 activity.20471467

 






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