NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Xanthatin

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

arachidonate 5-lipoxygenase

Pancreatic Cancer

PACA-2

61.95 µg/mL

-

-

-

Xanthatin inhibited 5-lipoxygenase activity

caspase 3, apoptosis-related cysteine peptidase

Pancreatic Cancer

PACA-2

-

-

-

-

Xanthatin induced a strong caspase 3 activity.

caspase 7, apoptosis-related cysteine peptidase

Pancreatic Cancer

PACA-2

-

-

-

-

Xanthatin induced a strong caspase 7 activity.

prostaglandin E receptor 3 (subtype EP3)

Pancreatic Cancer

PACA-2

-

-

-

-

the inhibition of PGE2 synthesis by xanthatin was assessed in MIA PaCa-2

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.