NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Wogonin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BAXBCL2-associated X protein581sarcomaS180----After the seven-day treatments by the route of i.v., wogonin (20, 40mg/kg) had significant inhibitory effect on the growth of inoculated S180 in mice. The inhibitory rates was 34.24%.After mice with S180 were treated with wogonin (20,40mg/kg) seven times intravenously,wogonin could increase the levels of bax mRNA and bax protein in a concentration-dependent manner.16755005

 






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