NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: toosendanin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CYCScytochrome c54205Rat pheochromocytomaPC-12----Toosendanin induced cytochrome c release from the mitochondria. As shown,cytochrome c in the cytosol of the cells could be detected since 24 h of treatment with toosendanin and lasted up to 72 h. These data indicated that cytochrome c release was involved in toosendanin-induced apoptosi.15297017

 






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