NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Tetrandrine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Colon CancerHT-29----Tetrandrine induced a decrease in procaspase 3 and an increase in cleaved, active caspase 3, and PARP was cleaved to its characteristic 85 kDa fragment, suggesting that tetrandrine caused caspase 3 activation and apoptosis.18437054

 






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