NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Squamocin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AURKBaurora kinase B9212Colon cancerSW-620----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of MSK1 in cancer cells and decreased the phosphorylated MSK1 (pMSK1).21299907
AURKBaurora kinase B9212Human Glioblastoma MultiformeGBM8401----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of MSK1 in cancer cells and decreased the phosphorylated MSK1 (pMSK1).21299907
AURKBaurora kinase B9212Liver CancerHUH7----Squamocin, isolated from several genera of the plant family Annonaceae, which decreased (m)RNA expression levels of MSK1 in cancer cells and decreased the phosphorylated MSK1 (pMSK1).21299907

 






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