NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Sesamin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
VEGFAvascular endothelial growth factor A7422Breast CarcinomaMDA-MB-231----inhibitory effect of sesamin on macrophage-induced VEGF expression was also observed with MDA-MB-231 cell.20617373
VEGFAvascular endothelial growth factor A7422Breast adenocarcinomaMCF-7----production of VEGF was significantly enhanced when MCF-7 cells were treated 24 h with MfCM compared with control treatment (454.5±81.2 vs. 207.9±50.6 pg/ml, P<0.05).20617373

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.