NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Sesamin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)4318Breast CarcinomaMDA-MB-231----inhibitory effect of sesamin on macrophage-induced MMP-9 expression was also observed with MDA-MB-231 cell.20617373
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)4318Breast adenocarcinomaMCF-7----MMP-9 mRNA expression was also induced in the MCF-7 cells after incubated with MfCM for 4 or 8 h, and sesamin was able to inhibit this MMP-9 mRNA induction.20617373

 






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