NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Saikosaponin D

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
FasTNF receptor superfamily, member 7355Lung adenocarcinomaA549----As observed in the induction of p21/WAF1, the expression of Fas/APO-1 was detected in A549 cells at 6 h after Saikosaponin D treatment. Maximum Fas/APO-1 was detected at 24 h. It is suggested that the induction of Fas/APO-1 in Saikosaponin D-treated A549 cells might be related to the activation of p53.15219811

 






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