NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Saikosaponin D

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Lung adenocarcinomaA549----Increase in p21/WAF1 protein was apparent at 6 h and reached maximum induction at 24 h in Saikosaponin D treated A549 cells. Moreover, the induction of p21/WAFr1 was in a dose-dependent manner.15219811

 






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