NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Rhinacanthin N

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Cervix AdenocarcinomaHela-S3----rhinacanthins-C and -N treatment caused the activation of caspase-3 in a dose-dependent manner after 48h exposure, whereas the activity was decreased at a highest concentration of rhinacanthin-Q. Rhinacanthin-N (90 mM), the most effective drug, induced a marked increase in caspase-3 activity to 2.5 fold over the control cells. .17015953

 






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