NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Psoralen

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NQO1NAD(P)H dehydrogenase, quinone 11728murine hepatoma cellHepa 1c1c7----psoralen significantly appeared 187% induction of QR activity compared to control without cytotoxicity at the concentration of 20 µg/mL and the concentration of 1.5 fold QR induction (1.5 FIC) of psoralen was 14.8 µg/mL.21468912
ODC1ornithine decarboxylase 14953Bladder CancerT24----psoralen significantly decreased by 63% and 41% on ODC activity compared to control without cytotoxicity at the concentration of 10 and 20 µg/mL, respectively and the half -maximal inhibition concentration (IC50) of psoralen was 15.6 µg/mL.21468912

 






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