| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 4790 | Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virus | RAW264.7 | - | - | - | - | Electrophoretic mobility shift assay EMSA, demonstrated a markedly reduced binding activity of NF-kappaB in nuclear extracts of pristimerin-treated cells. These results suggest that pristimerin inhibits the induction of inducible NO synthase by a mechanism which involves inhibition of NF-kappaB activation. | 9384235 |