NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Pinocembrin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CYCScytochrome c54205Neuroblastoma SH-SY5Y----Pinocembrin inhibit the release of cytochrome c from mitochondria to cytosol.18625218
CYCScytochrome c54205Colon cancerHCT-116----The release of cytochrome c is essential for the processing of initiator caspase-9 in mitochondria-mediated apoptotic signaling. The release of cytochrome c in to cytosol began after 24 h of pinocembrin and gradually increased to 72 h.17186548

 






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