NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Parthenolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Hepatocellular carcinomaSH-J1----Parthenolide is known as an inhibitor of NF- B via targeting of the I B kinase complex (7), and it subsequently prevents expression of NF- B-induced anti-apoptotic genes, including c-IAP1,c-IAP-2, TRAF1, TRAF2, Bfl-1/A1, Bcl-XL.12151389

 






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