NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Oleanolic acid

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Hepatocellular carcinomaHA22T----Oleanolic acid treatments concentration-dependently elevated caspase-3 activities .20005942
CASP3caspase 3, apoptosis-related cysteine peptidase836HepatomaHep-3B----Oleanolic acid treatments concentration-dependently elevated caspase-3 activities .20005942
CASP3caspase 3, apoptosis-related cysteine peptidase836HepatomaHep G2----Oleanolic acid treatments concentration-dependently elevated caspase-3 activities .20005942
CASP3caspase 3, apoptosis-related cysteine peptidase836Liver CancerHUH7----Oleanolic acid treatments concentration-dependently elevated caspase-3 activities .20005942
CASP8caspase 8, apoptosis-related cysteine peptidase841Hepatocellular carcinomaHA22T----Oleanolic acid treatments concentration-dependently elevated caspase-8 activities .20005942
CASP8caspase 8, apoptosis-related cysteine peptidase841HepatomaHep-3B----Oleanolic acid treatments concentration-dependently elevated caspase-8 activities .20005942
CASP8caspase 8, apoptosis-related cysteine peptidase841HepatomaHep G2----Oleanolic acid treatments concentration-dependently elevated caspase-8 activities .20005942
CASP8caspase 8, apoptosis-related cysteine peptidase841Liver CancerHUH7----Oleanolic acid treatments concentration-dependently elevated caspase-8 activities .20005942
ICAM1intercellular adhesion molecule 13383Hepatocellular carcinomaHA22T----Compound concentration-dependently inhibited cell adhesion and decreased ICAM-1 level.20005942
ICAM1intercellular adhesion molecule 13383HepatomaHep-3B----Compound concentration-dependently inhibited cell adhesion and decreased ICAM-1 level.20005942
ICAM1intercellular adhesion molecule 13383HepatomaHep G2----Compound concentration-dependently inhibited cell adhesion and decreased ICAM-1 level.20005942
ICAM1intercellular adhesion molecule 13383Liver CancerHUH7----Compound concentration-dependently inhibited cell adhesion and decreased ICAM-1 level.20005942

 






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