| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 | 2064 | Breast Carcinoma | MCNeuA | 15±4 µM | - | - | - | MCNeuA cells, a breast cancer cell line derived from transgenic mice overexpressing the rodent form of this receptor. Exposure of these cells to increasing concentrations of NDGA produced a dose-dependent inhibition of HER2/neu autophosphorylation. Ligand-independent tyrosine phosphorylation of HER2/neu was inhibited by NDGA with an IC50 of 15 ± 4 µM | 16142439 |