NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
NPACT
Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound:
N-n-octanoylnornicotine
Targets
Gene Name
Gene ID
Cancer
Cell Lines
IC
50
ED
50
EC
50
GI
50
Remark
References
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
1588
Breast Carcinoma
SK-BR-3
450 µM
-
-
-
Aromatase activity expressed by SK-BR-3 cells appeared to be sensitive to N-n-oct-anoylnornicotine (IC50 = 450 µM).
8313352
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
1588
Breast Carcinoma
MDA-MB-231
310 µM
-
-
-
Aromatase activity expressed by MDA-MB-231 cells appeared to be sensitive to N-n-oct-anoylnornicotine (IC50 = 310 µM).
8313352
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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.