NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Nimbolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a8797Colon cancerHCT-116----The limonoid up-regulated DR4 in HCT-116 cells in a dose- and time-dependent manner . Treatment of cells with 5 M nimbolide for 12 h was found optimal for up-regulating DRs without affecting cell viabilit.21078664

 






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