| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 1728 | Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virus | RAW264.7 | >50 µM | - | - | - | It induces the QR activity.Induction of phases 2 enzymes contributes to chemopreventive activity. QR is not catalyzing a conjugation reaction, but it is induced co-ordinately with other phase 2 enzymes and contributes to detoxification by reduction of reactive quinones to less reactive hydroquinones. | Phytochemistry Reviews 1: 369-377, 2002 |