| NOS2 | nitric oxide synthase 2, inducible | 4843 | Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virus | RAW264.7 | 12.9 µM | - | - | - | Nitric oxide (NO) synthase (iNOS) and consequently, enhance the generation of NO. Generally, NO is an important signaling molecule, long-term elevated levels of NO, however, have been linked to early steps in carcinogenesis.It cause inhibition of lipopolysaccharide (LPS)-mediated induction of inducible nitric oxide synthase , which is an anti-inflammatory mechanis. | Phytochemistry Reviews 1: 369-377, 2002 |