CASP3 | caspase 3, apoptosis-related cysteine peptidase | 836 | Colon Cancer | HT-29 | - | - | - | - | Increase in the active form of Caspase-3 was also observed at 12-72 h. PARP is a substrate of caspase-3 and Active caspase-3 can also catalyze DFF-45 and DFF-35. Cleavage of PARP and translocation of DFF-40 in nuclei indicate the activity of caspase-3 and also suggest the results of DNA fragmentation. | 18485277 |