| BCL2 | B-cell CLL/lymphoma 2 | 596 | Colon Cancer | HT-29 | - | - | - | - | nuclear full length PARP was decreased, and the cleaved form of PARP in the nuclei was significantly increased after 48 h of treatment .Similar results were obtained for the inhibition of Bcl-2 and pro-caspase-3 expression. During the apoptosis, PARP has been reported to be proteolyzed directly by active caspase-3, resulting in the inactivation of PARP for DNA repair. | 19477064 |