NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: mahanine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP9caspase 9, apoptosis-related cysteine peptidase842Human promyelocytic leukemiaHL-60----mahanine treatment resulted in time dependent increase in the proteolytic activity of various caspases in HL-60 cells by comparing the activity of each caspases in the control cells. Activity of caspase-9 slowly increased until 12 hr of mahanine treatment.t.14667927

 






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