NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Linalool

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN2Bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)1030LeukemiaMolt-4----treatment of Molt-4 leukemia cells with linalool (130 M) resulted in a time-dependent increase in mRNA expression of a variety of cyclin-dependent kinase inhibitors, such as p21Waf1/CIP1 (31.4 fold), p27Kip1 (43.0 fold), P57Kip2 (32.46 fold), p15 (4.0 fold) at 12 .19922762

 






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