NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Limonin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Colon CancerSW-480----limonin resulted in significant (P< 0.05) activation of caspase-3 by 3.5 fold higher compared to control, after 48 h of incubation. These results clearly suggest the involvement of caspase mediated apoptosis to inhibit the proliferation of colon cancer cells by limonoid.21338095

 






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