NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Limonin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Colon CancerSW-480----Reduced expression of antiapoptotic bcl2 was ob-served in cells incubated with limonin. Expression of Bcl2 was depleted by 30% in the case of limonin after 48 h.The ratio of Bcl2 to Bax was significantly lower (up to 9-fold), after 48 h of incubation with limoni.21338095

 






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