NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Licochalcone A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
RB1retinoblastoma 15925Gastric CancerAGS----Rb also play essential roles in the regulation of cell cycle. Licochalcone A treatment resulted in a dose-dependent increase in Rb and a decrease in MDM2 protein levels, suggesting that Licochalcone A may induce cell cycle arrest by affecting the levels of Rb in gastric cancer cells.21216524
RB1retinoblastoma 15925Gastric CancerMKN-28----Rb also play essential roles in the regulation of cell cycle. Licochalcone A treatment resulted in a dose-dependent increase in Rb and a decrease in MDM2 protein levels, suggesting that Licochalcone A may induce cell cycle arrest by affecting the levels of Rb in gastric cancer cells.21216524
RB1retinoblastoma 15925Gastric CancerMKN-45----Rb also play essential roles in the regulation of cell cycle. Licochalcone A treatment resulted in a dose-dependent increase in Rb and a decrease in MDM2 protein levels, suggesting that Licochalcone A may induce cell cycle arrest by affecting the levels of Rb in gastric cancer cells.21216524

 






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