NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Licochalcone A

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

CycB

Cyclin B

37618

Gastric Cancer

AGS

-

-

-

-

Treatment with Licochalcone A, resulted in a substantial reduction in the expression of cyclin B in MKN-45 and MKN-28 cells. These observations suggest that this decrease in cyclin B expression may play an important role inLicochalcone A-induced G2/M arrest in human gastric cancer cells.

21216524

CycB

Cyclin B

37618

Gastric Cancer

MKN-28

-

-

-

-

Treatment with Licochalcone A, resulted in a substantial reduction in the expression of cyclin B in MKN-45 and MKN-28 cells. These observations suggest that this decrease in cyclin B expression may play an important role inLicochalcone A-induced G2/M arrest in human gastric cancer cells.

21216524

CycB

Cyclin B

37618

Gastric Cancer

MKN-45

-

-

-

-

Treatment with Licochalcone A, resulted in a substantial reduction in the expression of cyclin B in MKN-45 and MKN-28 cells. These observations suggest that this decrease in cyclin B expression may play an important role inLicochalcone A-induced G2/M arrest in human gastric cancer cells.

21216524

Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.