NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Licochalcone A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Gastric CancerAGS----Exposure of gastric cancer cells to Licochalcone A resulted in a dose-dependent decrease in unactivated caspase-3. This indicates that the canonical mitochondrial apoptotic pathway is activated by Licochalcone A21216524
CASP3caspase 3, apoptosis-related cysteine peptidase836Gastric CancerMKN-28----Exposure of gastric cancer cells to Licochalcone A resulted in a dose-dependent decrease in unactivated caspase-3. This indicates that the canonical mitochondrial apoptotic pathway is activated by Licochalcone A21216524
CASP3caspase 3, apoptosis-related cysteine peptidase836Gastric CancerMKN-45----Exposure of gastric cancer cells to Licochalcone A resulted in a dose-dependent decrease in unactivated caspase-3. This indicates that the canonical mitochondrial apoptotic pathway is activated by Licochalcone A21216524

 






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