NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Licochalcone A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Prostate CancerLNCaP----Immunoblot analysis reveals that treatment with licorice in LNCaP cells down-regulated the expression of Bcl-2 with concomitant enhancement of the conversion of LC3-I to LC3-II, which is indicative of autophagic induction.19711916
BCL2B-cell CLL/lymphoma 2596Gastric CancerAGS----Licochalcone A-induced apoptosis by its effects on the expression of Bcl-221216524
BCL2B-cell CLL/lymphoma 2596Gastric CancerMKN-28----Licochalcone A-induced apoptosis by its effects on the expression of Bcl-221216524
BCL2B-cell CLL/lymphoma 2596Gastric CancerMKN-45----Licochalcone A-induced apoptosis by its effects on the expression of Bcl-221216524

 






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