NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Kaempferol

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cyclin-dependent kinase 1

Gastric Cancer

AGS

-

-

-

-

It reduces the protein level of cdc 2 in a dose-dependent manner.Decrease of cdc 2 expression might be a molecular mechanism through which flavonoids induce G2/M arrest.

cyclin-dependent kinase 1

Human Melanoma

OCM-1

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-

-

-

Kaempferol,inhibited CDK-1 by 50-70%.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.