NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Isoliquiritigenin

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

v-akt murine thymoma viral oncogene homolog 1

Prostate Cancer

DU-145

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Isoliquiritigenin inhibited both basal and EGF-induced phosphorylation of Akt. Western blot analyses revealed that treating DU145 cells with EGF led to increased phosphorylation of Akt.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.