NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Hesperidin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
ODC1ornithine decarboxylase 14953Colon carcinogenesis-----Flavonoids inhibit the growth of colonic ACF with more severe dysplastic or atypical hyperplastic epithelium (which may have a true preneoplastic nature) and suppressed progression of these lesions through adenoma to malignant neoplasm.Hesperidine either in alone or in combination with diosmin, found to block the induction of ODC in the colonic mucosa.9163681

 






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