NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Hesperetin

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cyclin D1

Breast adenocarcinoma

MCF-7

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It prevented the xenograft growth by down-regulating the expression of cyclin D.

cyclin D1

Breast adenocarcinoma

MCF-7

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The expression of cyclin D was inhibited after 48 h of 50 µM hesperetin.Hesperetin induced a decrease in cyclinD and CDK4, together with an increase in p21Cip1 and p27Kip1 associated with CDK4.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.