NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Hesperetin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCND1cyclin D1595Breast adenocarcinomaMCF-7----It prevented the xenograft growth by down-regulating the expression of cyclin D.22209285
CCND1cyclin D1595Breast adenocarcinomaMCF-7----The expression of cyclin D was inhibited after 48 h of 50 µM hesperetin.Hesperetin induced a decrease in cyclinD and CDK4, together with an increase in p21Cip1 and p27Kip1 associated with CDK4.17927510

 






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