NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Ginsenoside Rh1

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MAPK1mitogen-activated protein kinase 15594HepatomaHep G2----Rh1 treatment of HepG2 cells showed concentration-dependent inhibition of p38 MAPK phosphorylation, with the maximum inhibition at a concentration of 100 µM Rh.22314224
MAPK8mitogen-activated protein kinase 85599HepatomaHep G2----Rh1 treatment of HepG2 cells showed concentration-dependent inhibition of JNK1/2 phosphorylation, with the maximum inhibition at concentration of 100 µM.22314224
MMP1matrix metallopeptidase 1 (interstitial collagenase)4312HepatomaHep G2----Matrix metalloproteinase-1 (MMP-1) gene expression and its promoter activity were also concentration-dependently inhibited by Rh1 treatmen.22314224

 






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