NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Genistein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Pancreatic cancerCOLO 357----In vivo results were similar to in vitro findings, suggesting that the inactivation of NF-kappaB is at least one of the molecular mechanisms by which genistein potentiates gemcitabine-induced antitumor activity in experimental animal model16204081

 






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