NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Gallic acid

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)4318Gastric CancerAGS----MMP-2 activity was markedly reduced with GA. The inhibitory effects were more significant at concentrations of 2.5 and 3.5µM.GA presents a strong suppression on AGS cell growth and MMP secretion. GA possesses almost 600 times higher suppressive effect on MMP secretion than Caffic acid and Protocatechuic acid.20600540

 






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