NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Flavone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
RB1retinoblastoma 15925Lung adenocarcinomaA549----When A549 cells were exposed to 100 µM flavone for 12-48 h, the majority of the RB protein molecules was converted to the hypophosphorylated form. These results suggest that the G1 phase arrest caused by flavone is due to dephosphorylation of the RB protein.9804172

 






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