NQO1 | NAD(P)H dehydrogenase, quinone 1 | 1728 | Colon carcinogenesis | - | - | - | - | - | Ferulic acid(FA) administration at 100mg/kg dose signifcantly elevated QR activity in the colonic mucosa or liver (P< 0.02, P< 0<01, respectively). It significantly increased the activities of detoxification enzymes GST and QR in the liver and/or colonic mucosa. Thus, such evidence for the activity on the detoxifying enzymes may also be related to the blocking effect of FA on AOM-induced colon carcinogenesis. | 10893437 |