NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Eugenol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
E2F1E2F transcription factor 11869Melanoma WM1205Lu----cDNA array analysis showed that eugenol caused deregulation of the E2F family of transcription factors. Overexpression of E2F1 restored about 75% of proliferation ability in cultures. These results indicate that deregulation of E2F1 may be a D388key factor in eugenol-mediated melanoma growth inhibition both in vitro and in vivo.15574415

 






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