NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Eriocitrin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
ALOX5arachidonate 5-lipoxygenase240--29.1µmol/L---Eriocitrin isolated from the peel of Lumie fruit showed inhibitory activity against PMNL 5-LOX .From dose-response curves of eriocitrin,inhibited formation of 5-HETE is observed, and 5-LOX catalyses the intial step in the formation of 5-HETE and leukotrienes, which mediate allergic and inflammatory responses.J Sci Food Agric.,87:82-89.,2007

 






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