NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Eriocitrin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
ALOX12arachidonate 12-lipoxygenase239--22.3µmol/L---Eriocitrin isolated from the peel of Lumie fruit showed inhibitory activity against platelet 12-LOX .From dose-response curves of eriocitrin,inhibited formation of 12-HETE is observed, and Platelet 12-LOX catalyses the formation of 12-HETE, which is involved in atherosclerotic processes and tumour metastasis.J Sci Food Agric.,87:82-89.,2007

 






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