NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Daidzein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Human MelanomaOCM-1----Daidzein, which inhibited CDK2 and induced a G1 block, up-regulated p21CIP1.11322924
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Breast adenocarcinomaMCF-7----The serum metabolites of Puerariae radix inhibited cell proliferation via an up-regulation of p21/Waf1, p53, caspase-9, and Bax,as revealed by western blottin.19013426

 






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