| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 4313 | Murine melanoma | B16(F10) | - | - | - | - | Gelatin zymography of serum free culture medium of control (untreated) B16F10 showed presence of pro (72 kDa) and active (68 kDa)MMP-2.On treatment with curcumin(15mM),MMP-2 activity (both pro and active) was reduced after 3 - 6 days. Reduction of MMP-2 activity could be important reasons for anti-metastatic property of curcumin. | 15219947 |