NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Curcumin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
COX-2cytochrome c oxidase subunit II4513Colon CancerHT-29----Curcumin markedly inhibited COX-2 mRNA expression even at the 5 mM concentration after 6 h of treatment. Inhibition in COX-2 mRNA expression was also observed at higher concentrations (10-75 mM) of curcumin after 6 h of treatment. Maximum inhibition in COX-2 mRNA was observed at 75 mM curcumin.11566484

 






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