NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
NPACT
Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound:
Cucurbitacin Q
Targets
Gene Name
Gene ID
Cancer
Cell Lines
IC
50
ED
50
EC
50
GI
50
Remark
References
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
6774
Lung adenocarcinoma
A549
3.7±1.7 µM
-
-
-
Cuc Q suppressed the levels of P-STAT3 in A-549.
15735720
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
6774
Breast Carcinoma
MDA-MB-435
0.9±0.6 µM
-
-
-
Cucurbitacin Q treatment suppressed P-STAT3.
15735720
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
6774
Breast Carcinoma
MDA-MB-468
1.4±0.7 µM
-
-
-
Cucurbitacin Q treatment suppressed P-STAT3.
15735720
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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.